A patch which delivers a vaccine against Alzheimer's disease through the skin has been shown to be safe and effective, a study has found.
University of South Florida researchers reported the patch was able to clear brain-damaging plaques from mice.
They say it may be a simpler way of protecting people against the disease than a conventional injected vaccine.
UK experts said the Proceedings of the National Academy of Sciences study was "potentially very exciting".
Alzheimer's is linked with the build up of a protein called beta amyloid in the brain, where it clumps together to form damaging plaques.
A recently approved project of the sixth EU Framework Programme – MimoVax – is focussing on a new target for an Alzheimer's vaccine. The project, coordinated by the Austrian company Affiris GmbH, centres on the use of immune reactions to combat previously overlooked forms of the beta-amyloid that cause Alzheimer's disease. It is being run by seven partner organisations from three countries and has received an exceptionally positive response from Brussels – as well as Euro 2.4 million in financial support.